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Human IL-17AF Antibody ELISA Kit

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seat: Zhejiang
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Last update: 2017-11-03 20:33
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Product details


Brand

MultiSciences

Cat Num

70-EK1177

Product Name

Human IL-17AF ELISA Kit

Customs Name

Human IL-17AF ELISA Kit

Application

ELISA

Reactivity

Human

Assay Type

Sandwich ELISA

Suitable Sample Type

serum, plasma, cell culture supernates

Format

96-well strip plate

Storage

4 (unopened)standard stored at -20, others stored at 4 (opened)

Shipping Condition

4

Sample Volume

50 l

Sensitivity

10.24 pg/ml

Standard Curve Range

62.50 - 4000 pg/ml

Spike Recovery Range

92 % - 119 %

Mean Spike Recovery

1.04

CV of Intra plate

3.8 % - 4.5 %

CV of Inter plate

4.9 % - 7.0%

Components

96-well polystyrene microplate coated with a monoclonal antibody against IL-17AF
Human IL-17AF Standard, lyophilized
IL-17AF Detect Antibody
Standard Diluent
Streptavidin-HRP
Assay Buffer (10)
Substrate (TMB)
Stop Solution
Washing Buffer (20)
Plate Covers

Describtion

This assay employs the quantitative sandwich enzyme immunoassay technique for the quantitative detection of human IL-17AF. The Human IL-17AF ELISA is for research use only. Not for diagnostic or therapeutic procedures.
IL-17 family members are glycoproteins secreted as dimers that induce local cytokine production and recruit granulocytes to sites of inflammation. IL-17 is induced by IL-15 and IL-23, mainly in activated CD4+ T cells distinct from Th1 or Th2 cells. Of the six IL-17 family members, IL-17A and IL-17F share the strongest homology (50% amino acid identity) and the two genes are located in the same chromosomal region. IL-17A and IL-17F have been observed in tissue samples from various autoimmune diseases, such as rheumatoid arthritis, multiple sclerosis, psoriasis, inflammatory bowel disease, and asthma.
IL-17A expression is associated with many inflammatory diseases in humans, such as rheumatoid arthritis, multiple sclerosis, asthma, systemic lupus erythematosus, and allograft rejection. Expression of IL-17F is also linked with human inflammatory diseases, including asthma.

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